Herbert Y Meltzer Selected Research

Weight Gain

1/2020	Association between the -2548G/A polymorphism of the leptin gene and antipsychotic-induced weight gain: Analysis of the CATIE sample and meta-analysis.
10/2019	Genome-wide association study on antipsychotic-induced weight gain in Europeans and African-Americans.
1/2019	Genetic validation study of protein tyrosine phosphatase receptor type D (PTPRD) gene variants and risk for antipsychotic-induced weight gain.
1/2018	Impact of histamine receptors H1 and H3 polymorphisms on antipsychotic-induced weight gain.
1/2016	Association Study of Serotonin 3 Receptor Subunit Gene Variants in Antipsychotic-Induced Weight Gain.
1/2016	Association of orexin receptor polymorphisms with antipsychotic-induced weight gain.
8/2015	The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with increased body mass index and insulin resistance measures in bipolar disorder and schizophrenia.
2/2015	Association study of GABAA α2 receptor subunit gene variants in antipsychotic-associated weight gain.
1/2015	The role of genetic variation across IL-1β, IL-2, IL-6, and BDNF in antipsychotic-induced weight gain.
1/2015	Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes.

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Herbert Y Meltzer Research Topics

Disease

175	Schizophrenia (Dementia Praecox) 01/2022 - 03/2002
42	Psychotic Disorders (Schizoaffective Disorder) 01/2022 - 01/2002
41	Weight Gain 01/2020 - 01/2002
30	Cognitive Dysfunction 01/2021 - 03/2002
27	Tardive Dyskinesia 01/2021 - 07/2002
16	Treatment-Resistant Schizophrenia 01/2021 - 11/2003
12	Obesity 10/2019 - 08/2004
9	Bipolar Disorder (Manic Depressive Psychosis) 11/2019 - 09/2003
8	Dyskinesias (Dyskinesia) 10/2020 - 07/2003
6	Hallucinations (Hallucination) 01/2021 - 05/2003
6	Movement Disorders (Movement Disorder) 01/2021 - 09/2003
6	Parkinson Disease (Parkinson's Disease) 01/2020 - 07/2003
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 12/2005
5	Catalepsy 10/2017 - 05/2003
4	Body Weight (Weight, Body) 05/2014 - 01/2003
3	Memory Disorders (Memory Loss) 01/2022 - 02/2016
3	Mood Disorders (Mood Disorder) 01/2016 - 07/2003
3	Psychomotor Agitation (Akathisia) 12/2015 - 02/2010
3	Alzheimer Disease (Alzheimer's Disease) 12/2014 - 03/2002
3	Agranulocytosis (Granulocytopenia) 10/2012 - 09/2003
2	Torsades de Pointes (Torsade de Pointes) 03/2019 - 01/2002
2	Type 2 Diabetes Mellitus (MODY) 01/2019 - 09/2006
2	Weight Loss (Weight Reduction) 10/2017 - 05/2010
2	Neurobehavioral Manifestations 10/2017 - 02/2011
2	Substance-Related Disorders (Drug Abuse) 03/2015 - 08/2002
2	Inflammation (Inflammations) 05/2014 - 09/2010
2	Major Depressive Disorder (Major Depressive Disorders) 03/2009 - 07/2002

Drug/Important Bio-Agent (IBA)

133	Antipsychotic Agents (Antipsychotics)IBA 01/2022 - 01/2002
75	Clozapine (Clozaril)FDA LinkGeneric 01/2021 - 03/2002
39	Olanzapine (Zyprexa)FDA Link 01/2021 - 08/2002
23	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2021 - 09/2003
19	Dopamine (Intropin)FDA LinkGeneric 01/2021 - 08/2002
16	Phencyclidine (Angel Dust)IBA 01/2022 - 05/2003
10	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 03/2004
10	Pharmaceutical PreparationsIBA 01/2021 - 02/2008
10	Lurasidone Hydrochloride FDA Link 01/2021 - 09/2011
10	ziprasidone (Geodon)FDA Link 03/2019 - 10/2003
10	Haloperidol (Haldol)FDA LinkGeneric 01/2017 - 05/2004
10	Quetiapine Fumarate (Seroquel)FDA Link 03/2010 - 09/2003
9	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 08/2002
9	Cholinergic Agents (Cholinergics)IBA 12/2017 - 03/2002
9	N-Methylaspartate (NMDA)IBA 02/2017 - 05/2003
7	EnzymesIBA 10/2020 - 11/2005
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2011
7	Serotonin ReceptorsIBA 12/2013 - 03/2003
6	Aripiprazole (Abilify)FDA Link 01/2021 - 02/2007
6	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 01/2020 - 07/2003
6	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2019 - 07/2006
6	Proteins (Proteins, Gene)FDA Link 11/2018 - 03/2009
6	Brain-Derived Neurotrophic Factor (BDNF)IBA 08/2015 - 05/2009
5	metylperon (melperone)IBA 05/2020 - 01/2003
5	Neurotransmitter Agents (Neurotransmitter)IBA 01/2020 - 01/2003
5	Glutamic Acid (Glutamate)FDA Link 10/2018 - 09/2010
5	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2017 - 05/2008
5	Glucose (Dextrose)FDA LinkGeneric 10/2014 - 12/2005
4	norclozapineIBA 12/2017 - 04/2005
4	ProlactinIBA 01/2011 - 01/2003
4	Perphenazine (Trilafon)FDA LinkGeneric 01/2009 - 07/2006
3	Antidepressive Agents (Antidepressants)IBA 01/2022 - 08/2002
3	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2021 - 11/2018
3	pimavanserinIBA 01/2020 - 03/2010
3	cariprazineIBA 11/2019 - 12/2015
3	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2019 - 09/2007
3	gamma-Aminobutyric Acid (GABA)IBA 01/2016 - 01/2009
3	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 01/2016 - 04/2010
3	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2016 - 02/2007
3	Triglycerides (Triacylglycerol)IBA 08/2015 - 12/2011
3	5-HT2C Serotonin ReceptorIBA 03/2015 - 11/2010
3	tandospironeIBA 07/2013 - 05/2007
3	Adrenergic Agents (Adrenergic Drugs)IBA 08/2011 - 03/2003
3	Amino Acids FDA Link 02/2011 - 03/2004
3	AntioxidantsIBA 12/2009 - 11/2005
3	5-HT1A Serotonin ReceptorIBA 03/2009 - 01/2007
3	Glutamate Receptors (Glutamate Receptor)IBA 09/2005 - 05/2003
2	GLYX-13 peptideIBA 01/2022 - 02/2016
2	Vesicular Monoamine Transport Proteins (Vesicular Monoamine Transporter)IBA 01/2020 - 11/2013
2	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 12/2017 - 04/2005
2	CholesterolIBA 11/2017 - 12/2005
2	Amphetamine (Amfetamine)FDA LinkGeneric 10/2017 - 01/2009
2	lorcaserinIBA 10/2017 - 12/2013
2	Dopamine D4 Receptors (Dopamine D4 Receptor)IBA 01/2017 - 01/2017
2	Amisulpride (Solian)IBA 01/2017 - 07/2009
2	Ketamine FDA LinkGeneric 02/2016 - 11/2013
2	HDL CholesterolIBA 08/2015 - 12/2011
2	Biological ProductsIBA 06/2015 - 07/2014
2	Levodopa (L Dopa)FDA LinkGeneric 11/2014 - 04/2010
2	Dizocilpine Maleate (Dizocilpine)IBA 11/2013 - 02/2011
2	Buspirone (Buspar)FDA LinkGeneric 07/2013 - 09/2007
2	Serotonin 5-HT1 Receptor AgonistsIBA 05/2012 - 09/2007
2	Monoamine Oxidase (MAO)IBA 08/2011 - 05/2010
2	Oxytocin (Pitocin)FDA LinkGeneric 08/2010 - 07/2010
2	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 08/2010 - 06/2010
2	LipidsIBA 04/2010 - 01/2002
2	Glutathione Peroxidase GPX1IBA 12/2009 - 02/2006
2	asenapine FDA Link 11/2009 - 11/2008
2	perospironeIBA 12/2008 - 05/2007

Therapy/Procedure

7	Therapeutics 03/2016 - 01/2003
2	Injections 01/2018 - 08/2015
2	Drug Therapy (Chemotherapy) 02/2017 - 02/2007
2	Duration of Therapy 05/2014 - 02/2013